Wednesday, November 30, 2011

3D printer helps grow new bones

A 3D printer is being used to create "bone-like" material which researchers claim can be used to repair injuries.

The engineers say the substance can be added to damaged natural bone where it acts as a scaffold for new cells to grow.

It ultimately dissolves with "no apparent ill-effects", the team adds.

The researchers say doctors should be able to use the process to custom-order replacement bone tissue in a few years time.

Prof Susmita Bose helped carry out the work at Washington State University and co-authored a report in the Dental Materials journal.

"You can use the bone-like ceramic powder as a feed material and it can make whatever you draw on the computer," she says.

"It is mostly [suitable for] low load bearing applications. However, what we are trying to develop is the controlled degradation... of these scaffolds where as the scaffold dissolves in the body the bone tissue grows over it."

Binder

Prof Bose's team have spent four years developing the bone-like substance.

Their breakthrough came when they discovered a way to double the strength of the main ceramic powder - calcium phosphate - by adding silica and zinc oxide.

To create the scaffold shapes they customised a printer which had originally been designed to make three-dimensional metal objects.

It sprayed a plastic binder over the loose powder in layers half as thick as the width of a human hair.

The process was repeated layer by layer until completed, at which point the scaffold was dried, cleaned and then baked for two hours at 1250C (2282F).

Repairs

Tests carried on immature foetal bone cells in the laboratory found that new bone cells started growing over the scaffold within the first week of it being attached.

The team say they have also had promising results from tests involving live rabbits and rats.

"The way I envision it is that 10 to 20 years down the line, physicians and surgeons should be able to use these bone scaffolds along with some bone growth factors, whether it is for jaw bone fixation or spinal fusion fixation," says Dr Bose.

This is not the first time that orthopaedic experts have investigated the use of 3D printers.

Earlier this year a surgical trainee at Scotland's Monklands hospital detailed a technique to produce bone replicas using the technology.

Mark Frame suggested using a CAT scanner to produce images of damaged bones.

He said the data could then be fed into a 3D printer to create a model to help doctors plan their surgery.

He said the process cost about a tenth of traditional techniques.



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